منابع مشابه
Neurogenic Inflammation: Additional Points
William Meggs's recent article, "Neuro-genic Inflammation and Sensitivity to Environmental chemicals" (EHP 101:234-238), provides a useful introduction to a rapidly growing area of knowledge in physiology and posits a number of interesting hypotheses regarding the health effects of airborne chemicals. Some specific technical points, however, merit comment. Meggs describes the common chemical se...
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The Working Group on Neurogenic Inflammation proposed 11 testable hypotheses in the three domains of neurogenic inflammation, perceptual and central integration, and nonneurogenic inflammation. The working group selected the term people reporting chemical sensitivity (PRCS) to identify the primary subject group. In the domain of neurogenic inflammation, testable hypotheses included: PRCS have a...
متن کاملNeurogenic inflammation and allergy
Neurogenic inflammation encompasses a series of vascular and non-vascular inflammatory responses, triggered by the activation of primary sensory neurons with a subsequent release of inflammatory neuromediators, resulting in a neurally mediated immune inflammation. Neuromediators are mainly released from neurons. Immune and/or structural cells are secondary sources of these mediators during immu...
متن کاملNeutral endopeptidase modulates neurogenic inflammation.
A noncholinergic, nonadrenergic nervous system has been described, involving the sensory nerves in the airways. Chemicals, dusts and other irritants stimulate these sensory nerves to release substance P and related neuropeptides. These neuropeptides have the remarkable ability to affect multiple cells in the airways and to provoke many responses including cough, mucus secretion, smooth muscle c...
متن کاملNeurogenic inflammation in acute pancreatitis.
Acute pancreatitis is a clinical condition whose incidence has increased over the past few years. The exact mechanism of its development is not yet clear. Substance P, the proinflammatory neuropeptide, has a role in the initiation of neurogenic inflammation. Substance P and its receptor neurokinin-1 receptor (NK-1R) are involved in the development of local as well as systemic inflammation in ac...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1994
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.9410212a